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				<baseName xml:lang="en">2,2-Difluoroethanol</baseName>
				<baseName xml:lang="zh">2,2-二氟乙醇</baseName>
			</name>
			<common:synonyms xml:lang="en">Ethyl difluoroacetate; 2-Fluoroethanol; Fluoroacetate; Fluorocitrate</common:synonyms>
			<common:synonyms xml:lang="zh">Ethyl difluoroacetate; 2-Fluoroethanol; Fluoroacetate; Fluorocitrate</common:synonyms>
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			<CASNumber>359-13-7</CASNumber>
			<common:generalComment xml:lang="en">2,2-Difluoroethanol is used as a chemical intermediate. It has wide applications in medicine and fluoropolymers. Synthesis of 2,2-Difluoroethanol is from Ethyl difluoroacetate. 2-Fluoroethanol is converted by alcohol dehydrogenase (ADH) using nicotinamide adenine dinucleotide (NAD+) as cofactor, ultimately leading to the formation of fluoroacetaldehyde and then fluoroacetate. Fluoroacetate is a precursor to fluorocitrate, an inhibitor of aconitase, an enzyme that participates in the TCA cycle.</common:generalComment>
			<common:generalComment xml:lang="zh">2,2-Difluoroethanol 用作化学中间体。它在医药和含氟聚合物领域有着广泛的应用。2,2-二氟乙醇是由二氟乙酸乙酯合成的。2- 氟乙醇在醇脱氢酶（ADH）的作用下，以烟酰胺腺嘌呤二核苷酸（NAD+）为辅助因子进行转化，最终形成氟乙醛和氟乙酸酯。氟乙酸盐是氟柠檬酸盐的前体，而氟柠檬酸盐是参与 TCA 循环的一种酶--乌头酶的抑制剂。</common:generalComment>
			<sumFormula>C2H4F2O</sumFormula>
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